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Gene Hackman and Wife Dead in New Mexico; Rare Virus Linked to Tragic End

2025-03-25

Academy Award-winning actor Gene Hackman, 95, and his wife Betsy Arakawa, 65, were found deceased in their New Mexico home in late February. Medical investigators have determined that Arakawa’s death was caused by hantavirus pulmonary syndrome, a rare and potentially fatal respiratory condition contracted from rodents, while Hackman, who had long suffered from advanced Alzheimer’s disease, passed away days after her death.  

Authorities believe Arakawa likely died on February 11, with Hackman passing later on February 18 due to heart disease. His pacemaker last recorded irregular heart rhythms, identified as atrial fibrillation, before his death. Dr. Heather Jarrell, chief medical examiner of New Mexico, suggested Hackman may not have realized his wife had passed, leaving him alone and vulnerable during her absence.  

What is Hantavirus?  

Hantavirus is a rare infectious disease transmitted to humans through exposure to rodents, particularly contact with their urine, droppings, or saliva. In some cases, the virus can also spread via rodent bites or scratches. Although pets like cats and dogs are not directly susceptible to hantavirus, they can unknowingly bring infected rodents into homes, increasing the risk for their owners.  

Hantavirus occurs most frequently in rural areas such as farms and forests where rodents are prevalent, but it can also emerge in residential areas.  

How Rare is Hantavirus?  

Across the United States, hantavirus infections are uncommon. Since 1993, a total of 864 cases have been recorded, according to the Centers for Disease Control and Prevention (CDC). New Mexico has the highest number of reported cases, with 122 identified. Other states with notable occurrences include California, Washington, Arizona, and Colorado.  

Symptoms of Hantavirus  

Hantavirus can develop into two diseases: hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome. Arakawa succumbed to HPS, a severe lung disease known for its high mortality, claiming 36% of individuals who develop respiratory symptoms.  

Symptoms of HPS generally appear one to eight weeks after exposure to the virus and may include fever, fatigue, and muscle aches in large muscle groups, such as the thighs and back. As the illness progresses, fluid leakage into the lungs and severe respiratory distress often occur, leading to symptoms like coughing and shortness of breath within four to ten days. The virus can also damage the heart and cause shock.  

Currently, there is no specialized treatment for hantavirus. Management focuses on alleviating symptoms while avoiding complications. Severe cases often require hospitalization or intensive care for respiratory support.  

Preventing Hantavirus  

Combatting hantavirus starts with efforts to minimize rodent infestations. Homeowners should seal entry points where rodents could nest, especially in attics and basements. Persistent rodent problems may necessitate professional extermination services.  

During cleanup of rodent waste, precautions should be taken to prevent infection, such as wearing gloves and masks, ventilating affected areas, and disposing of waste outdoors. Washing hands thoroughly after handling contaminated materials is essential.  

Legacy and Risk  

The deaths of Gene Hackman and Betsy Arakawa serve as a poignant reminder of the rare but deadly risks posed by hantavirus. Hackman, an iconic star of Hollywood’s golden age, passed away under tragic circumstances just days after losing his wife. Experts urge vigilance in preventing rodent-related illnesses, particularly in rural environments where exposure risks are higher.  

While exceedingly uncommon, hantavirus remains a significant concern for public health officials, highlighting the importance of rodent control and awareness.


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