How to make powder from Angelica sinensis extract.

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Angelica sinensis extract

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1. Introduction to Angelica sinensis

Angelica sinensis, also known as "Danggui" in Chinese, is a well - known traditional Chinese medicinal herb. It has been used for thousands of years in traditional Chinese medicine (TCM) for its various health - promoting properties.

1.1 Botanical characteristics

Angelica sinensis is a perennial herb. It typically has a purplish - red stem and compound leaves. The plant can grow to a certain height, and its root is the main part used for medicinal purposes. The root is relatively thick, with a characteristic odor and taste.

1.2 Medicinal properties

It is believed to have the functions of nourishing blood, promoting blood circulation, and regulating menstruation. In TCM theory, it is often used to treat conditions related to blood deficiency, such as pale complexion, dizziness, and irregular menstruation. Modern research has also shown that Angelica sinensis may contain certain active ingredients that have antioxidant, anti - inflammatory, and immunomodulatory effects.

2. Extraction of Angelica sinensis

2.1 Preparation of raw materials

First, select high - quality Angelica sinensis roots. Ensure that they are clean, free from mold and other contaminants. Wash the roots thoroughly with clean water to remove dirt and impurities.

2.2 Drying process

After washing, the Angelica sinensis roots need to be dried. There are two common drying methods: natural drying and artificial drying. Natural drying is to place the roots in a well - ventilated and sunny place, but this method may take a longer time. Artificial drying can be carried out in a drying oven at a suitable temperature (usually around 40 - 60 °C) to speed up the drying process. The dried Angelica sinensis roots should be brittle and easy to grind.

2.3 Grinding of dried Angelica sinensis

Use a grinder or mortar and pestle to grind the dried Angelica sinensis roots into a fine powder. This powder is the basis for further extraction.

2.4 Extraction methods

There are several extraction methods available:

2.4.1 Solvent extraction

1. Select a suitable solvent, such as ethanol or water. Ethanol is often used because it can dissolve a wide range of active ingredients in Angelica sinensis.
2. Add the ground Angelica sinensis powder to the solvent in a certain ratio. For example, a ratio of 1:5 (powder:solvent) can be used.
3. Stir the mixture continuously for a certain period, usually several hours to ensure that the active ingredients are fully dissolved in the solvent.
4. Filter the mixture using a filter paper or a filtration device to separate the extract solution from the residue.

2.4.2 Supercritical fluid extraction

This is a more advanced extraction method. Supercritical carbon dioxide is often used as the extraction medium. It has the advantages of high extraction efficiency, good selectivity, and environmental friendliness. However, this method requires special equipment and higher costs.

3. Production of powder from Angelica sinensis extract

3.1 Concentration of the extract

After obtaining the extract solution, it is necessary to concentrate it. This can be done by using methods such as evaporation under reduced pressure. By reducing the pressure and heating slightly, the solvent in the extract solution can be evaporated, leaving a more concentrated extract.

3.2 Drying of the concentrated extract

There are different drying methods for the concentrated extract:

3.2.1 Spray drying

This method is suitable for large - scale production. The concentrated extract is sprayed into a hot air stream, and the solvent is rapidly evaporated, leaving dry powder particles. The advantage of spray drying is that it can produce fine and uniform powder with high production efficiency.

3.2.2 Freeze - drying

Also known as lyophilization. The concentrated extract is frozen first, and then the ice is directly sublimated under vacuum conditions. Freeze - drying can better preserve the active ingredients in the extract, but the equipment cost and energy consumption are relatively high.

3.3 Grinding and sieving of the dried extract powder

After drying, the obtained powder may need to be further ground to make it finer. Then, use a sieve to screen the powder to obtain a powder with a uniform particle size.

4. Quality control and safety considerations

4.1 Quality control

• Active ingredient content determination: Use appropriate analytical methods, such as high - performance liquid chromatography (HPLC), to determine the content of main active ingredients in the Angelica sinensis powder, such as ferulic acid. Ensure that the content meets the relevant standards.
• Purity inspection: Check for the presence of impurities, such as residual solvents, heavy metals, and pesticides. The content of these impurities should be within the allowable limits.
• Particle size analysis: Analyze the particle size distribution of the powder to ensure that it has a suitable particle size for its intended use.

4.2 Safety considerations

• When handling Angelica sinensis, ensure proper ventilation in the working environment, especially when using solvents for extraction, to avoid inhalation of harmful vapors.
• Follow strict safety procedures when using extraction and drying equipment to prevent accidents such as burns and electric shocks.
• For products intended for human consumption, ensure that all steps comply with relevant food and drug safety regulations.

5. Applications of Angelica sinensis extract powder

Angelica sinensis extract powder has a wide range of applications:

5.1 In the field of traditional Chinese medicine

It can be used to formulate traditional Chinese medicine prescriptions for treating various diseases related to blood deficiency and blood stasis. It can also be made into traditional Chinese medicine preparations such as pills, capsules, and tinctures.

5.2 In the field of cosmetics

Due to its antioxidant and skin - nourishing properties, it can be added to cosmetics such as creams, lotions, and masks to improve skin condition, such as enhancing skin elasticity and reducing wrinkles.

5.3 In the field of dietary supplements

It can be used as an ingredient in dietary supplements to provide health benefits such as blood nourishment and immune system enhancement for consumers.

6. Conclusion

Making powder from Angelica sinensis extract involves a series of steps from raw material preparation, extraction to powder production. Each step requires strict control to ensure the quality of the final product. With the increasing demand for natural products in various fields, Angelica sinensis extract powder has great potential for development. However, it is also necessary to pay attention to quality control and safety to meet the requirements of different applications.

FAQ:

What are the main properties of Angelica sinensis?

Angelica sinensis is a well - known herb in traditional medicine. It contains various bioactive compounds such as ferulic acid and ligustilide. These components are believed to have properties like anti - inflammatory, antioxidant, and potential benefits for women's health, such as regulating menstrual cycles.

What are the basic steps for extracting Angelica sinensis?

First, the Angelica sinensis material needs to be properly dried and crushed. Then, a suitable solvent, often ethanol or water - ethanol mixtures, is used for extraction. This can be done through methods like maceration (soaking the crushed material in the solvent for a period) or reflux extraction (heating the mixture in a reflux apparatus). After extraction, filtration is carried out to separate the extract from the solid residue.

How to ensure the quality of Angelica sinensis extract during the extraction process?

To ensure the quality, the source of Angelica sinensis should be reliable. Use high - quality raw materials. During extraction, control the extraction parameters precisely, such as the ratio of solvent to raw material, extraction time, and temperature. Also, proper storage of the extract after extraction is crucial to prevent degradation of its active components.

What equipment is needed to make powder from Angelica sinensis extract?

Typically, you would need equipment for drying the extract such as a freeze - dryer or a spray - dryer. A grinder or pulverizer is also necessary to turn the dried extract into powder. Additionally, for the extraction process itself, you may need containers for soaking or refluxing, and filtration equipment like funnels and filter papers.

Are there any safety precautions when making powder from Angelica sinensis extract?

Yes, there are. When using solvents for extraction, ensure proper ventilation as some solvents can be flammable or emit harmful vapors. Wear appropriate protective gear such as gloves and goggles. Also, make sure the equipment is clean and properly maintained to avoid contamination of the extract and the final powder product.

Related literature

• Studies on the Extraction and Pharmacological Activities of Angelica sinensis"
• "Optimization of the Powder - making Process from Angelica sinensis Extract"
• "The Chemical Components and Their Functions in Angelica sinensis Extract for Powder Preparation"